Polycystic kidney disease symptoms in a comprehensive development process

Polycystic kidney disease symptoms in a comprehensive development process
Polycystic kidney size and shape of a normal childhood, or slightly larger, the number and size of the cyst with age is gradually increasing and constantly increasing, the majority of cases to 40 to 50 years old kidney volume increased to a considerable extent before the onset of symptoms, mainly for two side kidney enlargement, kidney pain, hematuria, and hypertension.
Progress on both sides of nephropathy in renal enlargement 1. Asymmetry, there are differences in size, to the late two kidneys can fill the entire abdominal cavity, the surface of the cloth have a lot of kidney cysts, kidney-shaped so irregular, uneven, hard.
2 important symptom for kidney pain, and often lower back pressure or dull, but also pain, and sometimes abdominal pain, pain may be due to physical activity, walking for too long, such as sedentary exacerbated after bed reduce kidney bleeding, or infection stones move also unexpected pain causes.
3 Approximately half of the patients showed microscopic hematuria hematuria, may have episodes of gross hematuria, the Department of the cyst wall caused by ruptured blood vessels, bleeding for a long time can cause blood clots by ureteral colic, hematuria and proteinuria often accompanied by white blood cells in urine, urine protein less, generally no more than 1.0g / d, while pyuria kidney infection significantly, hematuria aggravated back pain with fever.
4 Hypertension is a common manifestation of ADPKD, not before serum creatinine increased, about half of high blood pressure, which oppressed the surrounding tissue cysts, activation of the renin - angiotensin - aldosterone system about the past 10 years, Graham PC, Torre V and Chapman AB confirmed the disease so normal kidney tissue, increased proximity between the cyst and cyst epithelial cells interstitial renin granules, and renin secretion, which is closely related to the growth of cysts and hypertension, in other words, appear high blood pressure cysts grow faster, can directly affect the prognosis.
5 renal insufficiency to happen sooner or later the disease renal insufficiency, individual cases that occur in adolescence renal failure, renal dysfunction rarely before the age of 40 and 70 years of age, about half remain renal function, but the development of hypertension to shorten the course of renal failure, there are also individual patients 80 years of age can maintain kidney function.
6 ADPKD patients with polycystic liver aged discovered how sac about half of the liver, about 70% after 60 years, it is generally believed that the slow development, and more about polycystic kidney disease 10 years later, the cyst is lost cholangiectasis made, in addition, pancreatic and ovarian cysts may also occur, colonic diverticulitis complicated by a high rate.
The clinical features of polycystic kidney disease:
Adult polycystic kidney disease symptoms usually appear in early adulthood, often with hematuria, the incidence of hypertension or renal dysfunction, abdominal palpation of polycystic kidney disease can be found in larger, mostly slowly progressive renal dysfunction, hypertension, obstructive or pyelonephritis, is an important reason for the acceleration of renal dysfunction, autosomal recessive type (infantile) polycystic kidney disease onset in infancy, clinical relatively rare, and more died in infancy, very few mild may live to adulthood.
Uremic anemia mild degree of anemia, the disease is often compared to other causes, the reason is generally kidney cysts can produce erythropoietin.

If you have any questions you can consult the online experts in Shijiazhuang Kidney Disease Hospital.